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ScheBo® · Biotech AG
Netanyastrasse 3
35394 Giessen
Germany

Phone +49 (0)641 / 4996-0
Fax +49 (0)641 / 4996-77
Email-contact

History

Foundation:

ScheBo® Biotech AG was founded in 1989 by the biochemists and molecular biologists Ursula Scheefers-Borchel, Ph.D., and Hans Scheefers, Ph.D.


Unique Selling Proposition:

Innovative diagnostics:

In 1993 ScheBo® Biotech AG launched worldwide the first non-invasive, cheap routine test procedure for monitoring the exocrine function of the pancreas. Today well reputed clinicians and medical text books regard the ScheBo® Pancreatic Elastase 1 ELISA, based on two monoclonal antibodies, as the "gold-standard" for non-invasive pancreatic exocrine function testing. ScheBo® Biotech AG is world market leader for this FDA-cleared product. Continuous innovation, strong customer focus and our problem solving philosophy have made ScheBo® Biotech AG a leading biopharmaceutical company.

Closing a gap:

In 1998 ScheBo® Biotech AG launched the ScheBo® Tumor M2-PK™ EDTA-Plasma Test, the first test worldwide that is able to detect a metabolic state, specific for 11 cancer entities, e.g. colon/rectum, gastric, pancreas, esophagus, breast, lung, prostate, kidney, renal, and cancer of the ovary. The predictive value of Tumor M2-PK reflects tumor activity and aggressiveness and gives clinicians additional information that is not provided by state of the art procedures. Thus, the ScheBo® Tumor M2-PK™ EDTA-Plasma Test closes a gap in the management of cancer treatment in clinical practice.

Fighting cancer, colorectal cancer screening:

In 2003 ScheBo® Biotech AG launched the ScheBo® Tumor M2-PK™ Stool Test, the first test detecting pyruvate kinase in stool, a new tool for colorectal cancer screening. This patented test is superior to the well-known occult blood stool tests. The new procedure has a sensitivity of 85% and a specificity of 83%. 2007 ScheBo® Biotech AG launched the ScheBo® M2-PK Quick™ Test, a worldwide new lateral flow test for colorectal cancer screening. Thereby ScheBo® Biotech AG hopes to be able to significantly improve colorectal cancer patients′ chances of being cured. The crucial element is a patented procedure for determining Tumor M2-PK in stool samples.

Fighting BSE:

In 2000 and 2004 ScheBo® Biotech AG launched different ScheBo® Brainostic™ Tests which allow the detection of brain and spinal cord (risk material) in meat products, thus providing optimal consumer protection. The patents for both, the GFAP- and NSE-based tests, are owned by ScheBo® Biotech AG.

Therapeutic cancer product focus:

ScheBo® Biotech AG possesses an excellent pipeline of novel, small anticancer drugs. The outstanding preclinical results already obtained will lead to clinical trials proving a worldwide novel cancer therapy strategy.


AEO-Certificate
The Main Customs Office of Giessen, Germany issued an AEO-F Certificate (Authorized Economic Operator – Customs Simplifications plus Security and Safety) to ScheBo Biotech AG on September 30, 2011.
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Lecture DDW 2011: New molecular markers: M2-PK
Lecture of Prof. Dr. Sybille Mazurek on WEO/OMED Colorectal Cancer Screening Committee Meeting DDW 2011.
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Biomarker ′M2-PK′ Identified as Key Enzyme in Cancer Diagnosis and Therapy
Ground Breaking Findings on Understanding Cancer Published in ′Science′
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Video: Focus 2010 lecture on M2-PK
The high sensitivity (c.80%) and high specificity (>90%) of the M2-PK stool test for colorectal cancer screening and detection, plus benefits for patients, laboratories and doctors, was presented at Focus 2010
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Tumour M2-PK as a stool marker for colorectal cancer
Comparative analysis in a large sample of unselected older adults vs colorectal cancer patients.
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Coeliac disease and pancreatic exocrine insufficiency
The data have shown that pancreatic insufficiency, demonstrated by low faecal pancreatic elastase-1 levels, is common in adult coeliac disease patients.
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ISO-Certificate
Our ISO-Cerficate as pdf-download.
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